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Interestingly, prolonged lack of sleep can cause oxidative stress and even hormone imbalances

Because LC can impair patients' ability to work, attend school, take care of family, and care for themselves, resulting in profound emotional and physical effects on the patients, their families, and caregivers ( Cost-effective, globally available, safe, and effective therapeutic interventions are warranted to ameliorate the morbidity and mortality of LC patients

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Tea and cardiovascular disease

While freezing did not impact the concentrations of NAD + , NADH, GSH, or GSSG, it triggered the conversion of NADPH to NADP + , with about 508% of NADP + originating from NADPH oxidation (Supplementary Figure 1m-r)